Rotting Eye Orc tribe
Once a prominent and infamous tribe, the Rotting Eye tribe has fallen on pretty rough times under it's current leader. Once numbering well over 800, the tribe is now down to ~120 Orcs. As a result, they are in a position where they could be annihilated or assimilated by another Orc tribe, if not wiped out by humans or some other, more monstrous enemy.
Of late, a group of Orcs from the Chaos Lands to the far northwest, have insinuated themselves into the tribe and even erected a small statue/shrine to Orcus. These "Black Orcs" are physically bigger and stronger than the rest of the Orcs, and have an unpredictable vicious temper to go with their great size. As such, the current Chieftain is hard-pressed and at a bit of a loss regarding how to deal with the Black Orcs. Until now he has only encouraged the tribe to remain true to He-Who-Watches, but it is clear to him that if he and perhaps his tribe is to survive, he must make a move soon.
The Chaos Lands
The center and seat of power of The Chaos Lands comprise all of what in standard Greyhawk, is Iuz and The Horned Society.
In addition, the following areas are under occupation/overrun:
Northern Furyondy north of the Crystal River
The Cold Marshes and southern Blackmoor
The eastern portion of the Wolf Nomads area (essentially everything directly north of the Vesve Forest)
The entirety of the Rovers of the Barrens
The Great Rift Canyon and Bandit Kingdoms
The entire area is occupied by demon worshiping humans, humanoids, and horrific monsters. Particularly strong cults include those of Orcus, Demogorgon, Kthulu, Thaumagorga, Xathoqqua, and Graz'zt. It is also rumored that there is active Devil worship going on is what was once more urban areas, with those cults trying to leverage the eventuality of Chaos undoing itself. Some areas of The Chaos Lands can be safely traversed by strong parties of humans, but large swathes of the lands are overrun by hordes of chaotic and evil beings, some of which are new to this world, and some of which come from the outside of Oerth, and aren't fit for man or beast.